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Advanced Healthcare Materials, 8 19 :e Petrou, Anastasios ; Granegger, Marcus ; Meboldt, Mirko ; Schmid Daners, Marianne A Versatile Hybrid Mock Circulation for Hydraulic Investigations of Active and Passive Cardiovascular Implants. ASAIO Journal, 65 5 Adel Fahmideh, Maral ; Lavebratt, Catharina ; Tettamanti, Giorgio ; Schüz, Joachim ; Röösli, Martin ; Kjaerheim, Kristina ; Grotzer, Michael A ; Johansen, Christoffer ; Kuehni, Claudia E ; Lannering, Birgitta ; Schmidt, Lisbeth S ; Darabi, Hatef ; Feychting, Maria A Weighted Genetic Risk Score of Adult Glioma Susceptibility Loci Associated with Pediatric Brain Tumor Risk.
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Nature Genetics, 51 6 Müller, Marion C ; Praz, Coraline R ; Sotiropoulos, Alexandros G ; Menardo, Fabrizio ; Kunz, Lukas ; Schudel, Seraina ; Oberhänsli, Simone ; Poretti, Manuel ; Wehrli, Andreas ; Bourras, Salim ; Keller, Beat ; Wicker, Thomas A chromosome-scale genome assembly reveals a highly dynamic effector repertoire of wheat powdery mildew. New Phytologist, 4 Schori, Christian ; Trachsel, Christian ; Grossmann, Jonas ; Barben, Maya ; Klee, Katrin ; Storti, Federica ; Samardzija, Marijana ; Grimm, Christian A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice.
Experimental Eye Research, A classic twin study of lower urinary tract obstruction: Report of 3 cases and literature review. Lower urinary tract symptoms, 11 2 :OO Durmaz, Esra ; Rajpurohit, Subhash ; Betancourt, Nicolas ; Fabian, Daniel K ; Kapun, Martin ; Schmidt, Paul ; Flatt, Thomas Evolution, 73 9 A clinical feasible method for computed tomography-based assessment of sarcopenia In patients with chronic pancreatitis. Pancreas, 48 10 A closer look at the relationship among accelerometer-based physical activity metrics: ICAD pooled data. International Journal of Behavioral Nutrition and Physical Activity, Massen, Jorg J M ; Behrens, Friederike ; Martin, Jordan S ; Stocker, Martina ; Brosnan, Sarah F A comparative approach to affect and cooperation.
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Infant Behavior and Development, Dunkel, Alexander ; Andrienko, Gennady ; Andrienko, Natalia ; Burghardt, Dirk ; Hauthal, Eva ; Purves, Ross S A conceptual framework for studying collective reactions to events in location-based social media. International Journal of Geographical Information Science, 33 4 Aczel, Balazs ; Szaszi, Barnabas ; Sarafoglou, Alexandra ; et al ; Freund, Alexandra M A consensus-based transparency checklist. Nature Human Behaviour, 4 1 A constitutive knockout of murine carbamoyl phosphate synthetase 1 results in death with marked hyperglutaminemia and hyperammonemia. Journal of Inherited Metabolic Disease, 42 6 Christen, Markus ; Alfano, Mark ; Robinson, Brian A cross-cultural assessment of the semantic dimensions of intellectual humility. A cross-sectional survey of coronary plaque composition in individuals on non-statin lipid lowering drug therapies and undergoing coronary computed tomography angiography.
Journal of Cardiovascular Computed Tomography, 13 2 Gerez, Juan A ; Prymaczok, Natalia C ; Rockenstein, Edward ; Herrmann, Uli S ; Schwarz, Petra ; Adame, Anthony ; Enchev, Radoslav I ; Courtheoux, Thibault ; Boersema, Paul J ; Riek, Roland ; Peter, Matthias ; Aguzzi, Adriano ; Masliah, Eliezer ; Picotti, Paola Science Translational Medicine, 11 :eaau Meuli, Martin ; Hartmann-Fritsch, Fabienne ; Hüging, Martina ; Marino, Daniela ; Saglini, Monia ; Hynes, Sally ; Neuhaus, Kathrin ; Manuel, Edith ; Middelkoop, Esther ; Reichmann, Ernst ; Schiestl, Clemens A cultured autologous dermo-epidermal skin substitute for full-thickness skin defects: a phase I, open, prospective clinical Trial in children.
Plastic and Reconstructive Surgery, 1 Faso, Carmen ; Hehl, Adrian B A cytonaut's guide to protein trafficking in Giardia lamblia. In: Ortega-Pierres, Guadalupe. Advances in Parasitology. United Stated of America: Elsevier, Weber, Samuel ; Beutel, Jan ; Da Forno, Reto ; Geiger, Alain ; Gruber, Stephan ; Gsell, Tonio ; Hasler, Andreas ; Keller, Matthias ; Lim, Roman ; Limpach, Philippe ; Meyer, Matthias ; Talzi, Igor ; Thiele, Lothar ; Tschudin, Christian ; Vieli, Andreas ; Vonder Mühll, Daniel ; Yücel, Mustafa A decade of detailed observations — in steep bedrock permafrost at the Matterhorn Hörnligrat Zermatt, CH. Earth System Science Data, 11 3 A deep learning framework for neuroscience.
Nature Neuroscience, 22 11 Dzudie, Anastase ; Kengne, Andre Pascal ; Lamont, Kim ; Dzekem, Bonaventure Suiru ; Aminde, Leopold Ndemnge ; Abanda, Martin Hongieh ; Thienemann, Friedrich ; Sliwa, Karen A diagnostic algorithm for pulmonary hypertension due to left heart disease in resource-limited settings: can busy clinicians adopt a simple, practical approach. Cardiovascular Journal of Africa, 30 1 Tait, Robert J ; Paz Castro, Raquel ; Kirkman, Jessica Jane Louise ; Moore, Jamie Christopher ; Schaub, Michael P Journal of Medical Internet Research, 21 9 :e De Lellis, Camillo ; De Rosa, Antonio ; Ghiraldin, Francesco A direct approach to the anisotropic Plateau problem. Advances in Calculus of Variations, 12 2 Ramos, Maria Ana Signum : Revista da ABREM, 20 2 A fibromyxoid stromal response is associated with muscle invasion in canine urothelial carcinoma.
Journal of Comparative Pathology, Konietzko, Uwe ; Gersbacher, Manuel T ; Streuli, Jeremy ; Krüger, Maik ; Thöni, Sarina ; Kins, Stefan ; Nitsch, Roger M A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites. Biological Chemistry, 9 A framework for the management of the pediatric airway. Paediatric Anaesthesia, 29 10 Smith, Daniel ; Dyble, Mark ; Major, Katie ; Page, Abigail E. A friend in need is a friend indeed: Need-based sharing, rather than cooperative assortment, predicts experimental resource transfers among Agta hunter-gatherers.
Evolution and Human Behavior, 40 1 Necula, Ciprian ; Drimus, Gabriel ; Farkas, Walter A general closed form option pricing formula. Review of Derivatives Research, Qian, Yong ; Piatkevich, Kiryl D ; Mc Larney, Benedict ; Abdelfattah, Ahmed S ; Mehta, Sohum ; Murdock, Mitchell H ; Gottschalk, Sven ; Molina, Rosana S ; Zhang, Wei ; Chen, Yingche ; Wu, Jiahui ; Drobizhev, Mikhail ; Hughes, Thomas E ; Zhang, Jin ; Schreiter, Eric R ; Shoham, Shy ; Razansky, Daniel ; Boyden, Edward S ; Campbell, Robert E A genetically encoded near-infrared fluorescent calcium ion indicator. Nature Methods, 16 2 Deplazes-Zemp, Anna A global biodiversity fund to implement distributive justice for genetic resources.
Developing World Bioethics, 19 4 Tian, Di ; Kattge, Jens ; Chen, Yahan ; Han, Wenxuan ; Luo, Yongkai ; He, Jinsheng ; Hu, Huifeng ; Tang, Zhiyao ; Ma, Suhui ; Yan, Zhengbing ; Lin, Quanhong ; Schmid, Bernhard ; Fang, Jingyun A global database of paired leaf nitrogen and phosphorus concentrations of terrestrial plants. Ecology, 9 :e Li, Jiancai ; Liu, Xiaoli ; Wang, Qi ; Huangfu, Jiayi ; Schuman, Meredith Christine ; Lou, Yonggen A group D MAPK protects plants from autotoxicity by suppressing herbivore-induced defense signaling. Plant Physiology, 4 Rampidis, Georgios P ; Benetos, Georgios ; Benz, Dominik C ; Giannopoulos, Andreas A ; Buechel, Ronny R A guide for Gensini Score calculation.
Atherosclerosis, Latzer, Michael ; Festic, Noemi A guideline for understanding and measuring algorithmic governance in everyday life. Internet Policy Review, 8 2 Schnegg-Kaufmann, Annatina ; Calzavarini, Sara ; Limacher, Andreas ; Mean, Marie ; Righini, Marc ; Staub, Daniel ; Beer, Juerg-Hans ; Frauchiger, Beat ; Osterwalder, Joseph ; Kucher, Nils ; Matter, Christian M ; Husmann, Marc ; Banyai, Martin ; Aschwanden, Markus ; Mazzolai, Lucia ; Hugli, Oliver ; Nagler, Michael ; Daskalakis, Michael ; Rodondi, Nicolas ; Aujesky, Drahomir ; Angelillo-Scherrer, Anne A high Gas6 level in plasma predicts venous thromboembolism recurrence, major bleeding and mortality in the elderly: a prospective multicenter cohort study.
Journal of Thrombosis and Haemostasis, 17 2 Varadharajan, Srinidhi ; Rastas, Pasi ; Löytynoja, Ari ; Matschiner, Michael ; Calboli, Federico C F ; Guo, Baocheng ; Nederbragt, Alexander J ; Jakobsen, Kjetill S ; Merilä, Juha A high-quality assembly of the nine-spined stickleback Pungitius pungitius genome. Genome Biology and Evolution, 11 11 Song, Yuanbin ; Rongvaux, Anthony ; Taylor, Ashley ; Jiang, Tingting ; Tebaldi, Toma ; Balasubramanian, Kunthavai ; Bagale, Arun ; Terzi, Yunus Kasim ; Gbyli, Rana ; Wang, Xiaman ; Fu, Xiaoying ; Gao, Yimeng ; Zhao, Jun ; Podoltsev, Nikolai ; Xu, Mina ; Neparidze, Natalia ; Wong, Ellice ; Torres, Richard ; Bruscia, Emanuela M ; Kluger, Yuval ; Manz, Markus G ; Flavell, Richard A ; Halene, Stephanie A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies. Soneson, Charlotte ; Love, Michael I ; Patro, Rob ; Hussain, Shobbir ; Malhotra, Dheeraj ; Robinson, Mark D A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs.
Life Science Alliance, 2 1 :e A kinetic model for Brain-Derived Neurotrophic Factor mediated spike timing-dependent LTP. PLoS Computational Biology, 15 4 :e Scheyer, Torsten M ; Neuman, Andrew G ; Brinkman, Donald B A large marine eosauropterygian reptile with affinities to nothosauroid diapsids from the Early Triassic of British Columbia, Canada. Acta Palaeontologica Polonica, Sharir, Amnon ; Marangoni, Pauline ; Zilionis, Rapolas ; Wan, Mian ; Wald, Tomas ; Hu, Jimmy K ; Kawaguchi, Kyogo ; Castillo-Azofeifa, David ; Epstein, Leo ; Harrington, Kyle ; Pagella, Pierfrancesco ; Mitsiadis, Thimios ; Siebel, Christian W ; Klein, Allon M ; Klein, Ophir D A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nature Cell Biology, 21 9 Vassallo, Carmine ; Grano, Giovanni ; Palomba, Fabio ; Gall, Harald C ; Bacchelli, Alberto A large-scale empirical exploration on refactoring activities in open source software projects.
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Der Bewegungsmechanismus der Perlen wurde experimentell ermittelt. Der Nachweis des Schwingungscharakters der Bewegungen wurde durch Widerstandsmessungen, Tropfversuche und optische Messergebnisse erbracht. ERDMANN nennt sie Pisolithe. Hierunter werden jedoch von anderen Autoren alle Ooide mit einem Durchmesser Uber 2 mm verstanden, oder auch Ooide heisser Quellen KUMM Definition der Spelaeoide : Deri v atio nominis : spSlaion griech. Der Verfasser dankt Herrn Prof. SOLLE und Herrn Dr. Dank dem Entgegenkommen der Herren Dr. FRANKE Kreuzpul 1 ach und Herrn Dr. FRANZ und L. FRICK Darmstadt. HESS, F. BLATTER, I. Literatur: CAROZZI, A. I Microscopic sedimentary petrography. S OTTEMANN, J. Wien, math. Wien, mathem. I, , H. S SLOSS, L. I COOMBS, H. Akten 3. Wien Obertraun Salzburg , Bd. C, , 20 Abb.
HOHMANN: Die erste Frage kann dahingehend klar beantwortet werden, dass es in einem Nest unter normalen Voraussetzungen keine losen Spelaeoide gibt, die ihr Wachstum abgebrochen haben. Derartige Schnitte bildet z. KUNSKY ab. Untersuchungen von P. WEYL mit dem "Saturometer" zeigten, dass Anlagerung von CaC 03 nur stattfindet, wenn die Ooide in Bewegung sind. Rotationsbewegungen sind nicht notwendig. Hafl HGKOXOpyhM coflflHOKynoflbHbinM cxpyKxypaMM Ha nosepxHocxM pacnoflararaxcfl noflorne flenpeccMM. Uki paSHOipaBHUkl JlGC. B pG3yflbT3TG Fp O F M 6 3 FA3CT0B H3A FOflSGMHOM FOflOCTbHD.
HESS, Jr. Department of Geology and Geophysics, Pennsylvania State University, University Park, U. NEVIN W. DAVIS HRB Sirg-r, Inc. State College, U. ABSTRACT The Butler Cave Sinking Creek System was discovered in the spring of by Kennedy Nicholson. Since then thousands of man-hours have been spent in the exploration and study of the cave system by various groups and individuals. The cave is developed in the Tonsloway and Keyser Limestones of Silurian age in the Ridge and Valley Province of the Appalachian Mountains in Virginia. Development of the cave is stratigraphically controlled and follows the structure of the enclosing limestones and sandstones. Major development is on both sides of the lower Breathing sandstone and along the plunging Burnsville Cove Synclinal axis.
The discovery was made by Kennedy Nicholson when he dug open a small hole from which a strong draft of air flowed. The existence of a large cave system had been suspected for many years. The drainage in Burnsville Cove is subsurface; all of the drainage from both Chestnut Ridge and Jack Mountain disappears underground. Along the Bullpasture River 5. All of these are shown in Figure 1 along with their geographic relationship to the Cove and surrounding mountains. The Cove contains many large and small sinkholes within these limestones, many of which serve as inputs for the water to the cave systems. The Butler Cave Sinking Creek System, hereafter referred to as the Sinking Creek System, is located within the Burnsville Cove on the USGS Wil 1 i a msvil 1 e 15 minute Quadrangle in Bath county. The cave system with its See Figure 1 for a map of the area showing the location of the cave entrances.
The entrance to the Sinking Creek System is under a sandy ledge on the west side of a large sink 1 28 km north of Burnsville and 2. The entrance is a chance opening on the western limb of the Burnsville Syncline and is located where erosion has cut into the end of a joint passage. Major development is on bath sides of the lower Breathing sandstone and along the Burnsville Cove Synclinal axis. Stratigraphy Sedimentary rocks of lower Silurian to middle Devonian Age are exposed in the Burnsville Cove area. The stratigraphic section is illustrated in Figure 2. A general description of the Tonoloway and Keyser Limestones foilows. The laminea within the limestone appears to be thin shale beds and red mudstone beds. Figures of the Virginia Geological Survey indicate that the Tonoloway might be to meters thick in the area.
According to Oeike the formation as measured in the Sullpasture Gorge is meters thick. Much of the Sinking Creek System is developed in the upper 30 meters of the formation. Keyser Limestone Conformably overlying the Tonoloway Limestone is the Keyser Limestone. Oeike indicates that the formation is 65 meters thick in the Burnsville Cave. To the south in the Appalachian Hountain belt most of the Keyser Limestone is replaced by the Clifton Forge Sandstone. Tongues of this sandstone extend into the Burnsville Cove forming the upper and lower Breathing sandstones. At the Sinking Creek System these sandstone and sandy limestone beds are found about 24 meters apart. The lower Breathing sandstone is 3. The upper meter is a sandy limestone and the lower part is a sandstone of sub-rounded quartz grains cemented with calcite.
Oue to the solubility of the calcitic cement, this calcareous sandstone bed is penetrated in many places within the Sinking Creek System. The upper Breathing sandstone as described by Deike is 3. The upper meter is calcareous. The lower part is a medium to coarse grained orthoquartizite cemented with quartz overgrowths on the grains. It is non-soluble but is penetrated at collapses. The major structures are large parallel folds striking about f. Burnsville Cove is developed on a plunging syncline with Tower Hill and Bullpasture Mountain to the southeast and Jack Mountain to the northwest, both anticlinal structures. Figure 3 shows a section through the Cove. Superimposed an the Burnsville Cove Syncline are several minor folds.
In the southwest Chestnut Bidge, an anticline which divides the major syncline, is complicated by a syncline in its crest. Northeast of the Water Sinks this anticline is divided into three anticlines and two minor synclines Deike, Within the thinbedded limestones exposed in the Cove and in the cave there are minor folds with magnitudes ranging from a few centimeters to 10 meters. Jointing is an important control on the solution of limestone. Adcording to Deike , the mest prominent joints strike N50 W, which is the regional dip joint. The main stream trunk channel in the Sinking Creek System follows this joint set, while the upstream section is on a third prominent joint set striking N60 E. Figure 4 is a rosette of the joints measured in the Burnsville Cove by Deike As seen in Figure 5, the cave system consists of a main trunk channel following the plunging Burnsville Synclinal axis and a network of side caves developed on both flanks of the syncline which connect at or above grade.
Sinking Creek and Sneaky Creek, two vadose streams, both flow along this passage.. Upstream from Sinking Creek the trunk channel is dry except under flood conditions. The main trunk channel is 10 to 20 meters high and wide and may be characterized as having long expanses of flat unsupported ceilings and level boulder and cobble floors. Upstream the trunk channel terminates by breaking up into several smaller stream canyon passages which are terminated in fill. Downstream the trunk channel naroows into parallel stream canyons developed on two levels; i. The streams continue through siphons and finally resurge in Lockridge Aqua Spring 4.
There are several side caves on both sides of the trunk channel which drain down dip into it. These side caves consist of a network of passages developed on the regional dip and strike joint sets and a joint set striking E. They can best be described as a maze of parallel passages and multiple levels with minor folding playing a small role in their development. The passages range from narrow stream canyons to large secondary trunk channels. Breathing Cave can also be considered a side cave of the Sinking Creek System. Although it is not presently connected by traversable passage to it, it is geologically related.
The waters from Breathing connect with those from the Sinking Creek System. The upper and lower Breathing sandstones acted as confining layers in the development of the Sinking Creek System. Developed in the 24 meters of Keyser Limestone between the two sandstones are the entrance section, the Sneaky and Slippery Creek sections, possibly Mbogintao Land, and Breathing Cave. The rest of the cave, i e. The upper sandstone is non-calcareous and acted as the upper limit to solution far the entire cave system. It is known to be penetrated only in areas of massive collapse.
Water does, however, seep through along joints which go through the sandstone. The lower Breathing sandstone is calcareous and has been penetrated by both collapse and solution. This has allowed the connection of the various sections of the cave. In the downstream reaches of the cave, passage has developed on both sides of the lower sandstone which has resulted in Marlboro Country underlying the Sneaking and Slippery Creek sections. The lower Breathing sands tone, has, therefore, ' r ; acted as both an upper and lower limit to solution. The same thing has possibly occurred in the upstream section where Mbogintao Land overlies Huntley's Cave, and Boundless Cave, presently a separate cave, appears to overlie part of the Sinking Creek System.
The hydrology of the Burnsville Cove area is complex with both surface and subsurface drainage. The resurgence for the Sinking Creek System is Lockridge Aqua Cave and Spring located along the Bullpasture River see Figure 1 4,0 km from the end of the humanly passable passage. Lockridge Aqua is within the Keyser Limestone and has an average flow of liters per second. The combined flows of the streams in the Sinking Creek System, including Breathing Cave, account for most of the flow of Lockridge Aqua SprSng. Other known inputs to Lockridge Aqua are the surface Sinking Creek and most likely the Water Sinks. The overall hydrology of the cave system and cove is just now coming to light as work is presently being done an tracing the various cave and surface streams. The Sinking Creek System is, therefore, primarily a trunk channel developed along the axis of the plunging Burnsvi 11 e.
Development is joint controlled with the upper and lower Breathing sandstones acting as limits to solution. Lockridge Aqua Cave and Spring serves as the resurgence for the waters from the Sinking Creek System, Breathing Cave and surface Sinking Creek. FUTURE WORK Projects in progress at the present time under the direction of the Butler Cave Conservation Society are an attempt to connect the Sinking Creek System and Breathing Cave, completion of the mapping of the cave system which has a potential to double its Preliminary work points to the existence of two more large cave systems in the Cove. Water sinking at Cycle Sink resurges 3. Q km away and meters lower. These water sinks and resurgences are shown in Figure 1. Survey Butts, Charles, Geology of the Appalachian Valley in Virginia, Part 1: Va.
Survey Bull. Thesis, University of Missouri. HESS: The main channel in Butler Cave does follow the plunging synclinal axis. It is younger and has had vadose modification. Many of the side passages do not meet the main channel at grade, they meet above grade. The rectangular network passage pattern af the rest of the system is of artesian origin. The authsr paints eut the regularity af the even strata: lower Coral Limestone, G. The most erosive layer is that of Globerina Limestone, but caves are found in all layers, yet will easily collapse in e.
Blue Clay. Most caves are abrasive phenomena along the coast, but there are some real corrosive caves in the interior of the two greater islands, Malta and Gozo. The most interesting cave is Ghar Dal am, which is 20Q m long and possesses a remarkable paleontological bone brecchia. Auf der Hauptinsel Malta ist der Globerinenkalk vorwiegend. Bisweilen brechen die Wellen durch die Platte und brausen wie Strandquellen auf. LutHiaapt Ist dSSfs, . Mur wo es eine tiefe Ausgrabung gibt z. Sogar die gewaltigen Erdbeben in Kalabrien und Sizilien am Eins solche Pforte ist in den Hergelfelsen W. Sinterschmuck ist selten und besteht wesentlich aus Deckenund Wandsinter. Sie liegt in einer geographisch-geologischen Zone "Collapsed Upper Limestone" und weist einen Einsturz oder eine Verwerfung auf. Paul Faure 1. Das Terrain ist eine typische Karstlandschaft ca.
Han merkt drei verschiedene Horizonte oder Peneplains. Hinter der Aussenwand aus Korallenkalk ist eine Zone von Globerinenkal k, und das turbulente Wasser einer ehemaligen Regression hat sin tiefes unterirdisches Bassin dort ausgegraben, wo sich die weltbekannte Knochenbrecchia befindet. Zwergelefant und Nashorn, die von Th. Vom Regressionswasser, das lokal seht heftig werden konnte, sind die Reste dann mitgeschleppt worden. Nach m biegt der Hauptgang etwas rechts ab, und die Feuchtigkeit und der Gehalt von CO 2 macht das Atmen immer schwieriger. Bei meinem Besuch habe ich eine Aussentemperatur von 26 C, von 23 C 10 m im Inneren und 17 m im Inneren notiert, und der Barometerstand war gleichzeitig resp. Literatur: 1. Faure, P, , 2. Furon, R.
Glze, B. Hadding, A. S ympos. Varenna , Cens The prequaternary sedimentary Rock of Sweden, T. VI Reef Limestones Lund X Leipzig 5. Geology of the Maltese Island, Malta 6. Malta PB Exploration Co. Tell, L. C orrespond. Zwar hat man sich in der letzten Zeit z. B, in weichen Kalksteinen, weil sie in Granit, Gneis u.